Package: tipmap 0.5.3

Christian Stock

tipmap: Tipping Point Analysis for Bayesian Dynamic Borrowing

Tipping point analysis for clinical trials that employ Bayesian dynamic borrowing via robust meta-analytic predictive (MAP) priors. Further functions facilitate expert elicitation of a primary weight of the informative component of the robust MAP prior and computation of operating characteristics. Intended use is the planning, analysis and interpretation of extrapolation studies in pediatric drug development, but applicability is generally wider.

Authors:Christian Stock [aut, cre], Morten Dreher [aut], Emma Torrini [ctb], Boehringer Ingelheim Pharma GmbH & Co. KG [cph, fnd]

tipmap_0.5.3.tar.gz
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tipmap.pdf |tipmap.html✨
tipmap/json (API)
NEWS

# Install 'tipmap' in R:
install.packages('tipmap', repos = c('https://boehringer-ingelheim.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Bug tracker:https://github.com/boehringer-ingelheim/tipmap/issues

On CRAN:

bayesian-borrowingbayesian-methodsclinical-trialevidence-synthesisextrapolationpediatricspharmaceutical-developmentprior-elicitationtipping-pointweighting

17 exports 1 stars 1.10 score 74 dependencies 12 scripts 221 downloads

Last updated 6 months agofrom:99e6c7c65d. Checks:OK: 7. Indexed: yes.

TargetResultDate
Doc / VignettesOKSep 01 2024
R-4.5-winOKSep 01 2024
R-4.5-linuxOKSep 01 2024
R-4.4-winOKSep 01 2024
R-4.4-macOKSep 01 2024
R-4.3-winOKSep 01 2024
R-4.3-macOKSep 01 2024

Exports:create_new_trial_datacreate_posterior_datacreate_prior_datacreate_tipmap_datadraw_beta_mixture_nsamplesfit_beta_1expfit_beta_mult_expget_cum_probs_1expget_model_input_1expget_posterior_by_weightget_summary_mult_expget_tipping_pointsload_tipmap_dataoc_biasoc_coverageoc_postipmap_plot

Dependencies:abindassertthatbackportsbayesplotBHcallrcheckmateclicodacodetoolscolorspacedescdigestdistributionaldplyrfansifarverFormulafurrrfuturegenericsggplot2ggridgesglobalsgluegridExtragtableinlineisobandlabelinglatticelifecyclelistenvloomagrittrMASSMatrixmatrixStatsmgcvmunsellmvtnormnlmenumDerivparallellypillarpkgbuildpkgconfigplyrposteriorprocessxpspurrrQuickJSRR6RBesTRColorBrewerRcppRcppEigenRcppParallelreshape2rlangrstanrstantoolsscalesStanHeadersstringistringrtensorAtibbletidyselectutf8vctrsviridisLitewithr

Specifying a primary weight of the informative prior component

Christian Stock

Rendered fromexpert_elicitation.Rmdusingknitr::rmarkdownon Sep 01 2024.

Last update: 2023-07-26
Started: 2023-04-20

Introduction to the 'tipmap' package

Christian Stock

Rendered fromintroduction.Rmdusingknitr::rmarkdownon Sep 01 2024.

Last update: 2024-02-08
Started: 2023-01-28