Package: bhmbasket
Title: Bayesian Hierarchical Models for Basket Trials
Version: 1.1.0
Authors@R: 
  c(
    person(given = 'Stephan',
           family = 'Wojciekowski',
           role = c('aut', 'cre'),
           email = 'stephan.wojciekowski@boehringer-ingelheim.com'),
    person(given = 'Tathagata',
           family = 'Chattopadhyay',
           role = 'aut',
           email = 'tchattopadhyay6@gmail.com'))
Description: Provides functions for the evaluation of basket trial
        designs with binary endpoints. Operating characteristics of a
        basket trial design are assessed by simulating trial data
        according to scenarios, analyzing the data with Bayesian
        hierarchical models (BHMs), and assessing decision
        probabilities on stratum and trial-level based on Go / No-go
        decision making. The package is build for high flexibility
        regarding decision rules, number of interim analyses, number of
        strata, and recruitment. The BHMs proposed by Berry et al.
        (2013) <doi:10.1177/1740774513497539> and Neuenschwander et al.
        (2016) <doi:10.1002/pst.1730>, as well as a model that combines
        both approaches are implemented. Functions are provided to
        implement Bayesian decision rules as for example proposed by
        Fisch et al. (2015) <doi:10.1177/2168479014533970>. In
        addition, posterior point estimates (mean/median) and credible
        intervals for response rates and some model parameters can be
        calculated. For simulated trial data, bias and mean squared
        errors of posterior point estimates for response rates can be
        provided.
License: GPL-3
URL: https://CRAN.R-project.org/package=bhmbasket,
        https://github.com/Boehringer-Ingelheim/bhmbasket
BugReports: https://github.com/Boehringer-Ingelheim/bhmbasket/issues
Depends: R (>= 3.6.0)
Imports: foreach, doRNG, rjags, checkmate
Suggests: doFuture, future, knitr, rmarkdown, RBesT, testthat (>=
        3.0.0)
VignetteBuilder: knitr
Encoding: UTF-8
RoxygenNote: 7.3.2
Language: en-US
SystemRequirements: JAGS 4.x.y (http://mcmc-jags.sourceforge.net)
Config/testthat/edition: 3
Config/pak/sysreqs: jags
Repository: https://boehringer-ingelheim.r-universe.dev
Date/Publication: 2026-04-14 11:40:22 UTC
RemoteUrl: https://github.com/boehringer-ingelheim/bhmbasket
RemoteRef: HEAD
RemoteSha: d9d79abcc885c98d84cc7eb2b766988474c8a1f7
NeedsCompilation: no
Packaged: 2026-06-13 07:50:40 UTC; root
Author: Stephan Wojciekowski [aut, cre],
  Tathagata Chattopadhyay [aut]
Maintainer: Stephan Wojciekowski <stephan.wojciekowski@boehringer-ingelheim.com>